A caution not to use the domperidone generic drug Motilium, prescribe and sold in Cameroon, is being shared on Facebook by Cameroonians. The caution warns that the medicine has been the cause of many children’s death.
Motilium is generally prescribed to relieve the symptoms of the slowdown in the movement of the gastrointestinal tract (associated with diabetes and gastritis) and cases of the gastroesophageal reflux.
However, a research conducted in 2005 and a reassessment of the benefit/risk conducted in 2014 by The European Agency for the Evaluation of Medicinal Products pointed out its clinical inefficiency. They also warned of risks of heart diseases or sudden death.
So, though there are no figures to prove the risks in Cameroon, the research made by Canadians and Europeans justified that there is an increase ( between 1.6% and 3.7%) of sudden deaths among people who use domperidone.
So, it is risky to use Motilium; the medicine is even riskier for older people, for people who combine it with other medicine which can modify the electrical activities of their heart or even when the percentage of domperidone is high in the blood system (20-30 mg).
Moreover, in 2012, the medical journal Prescrire said that there was evidence of some 25 to 123 deaths due to Motilium and, this year, the journal includes Motilium on its list of the 91 medicines which do more harm than good.
Furthermore, in September 2014, the European Agency for the Evaluation of Medicinal recommended the removal of Motilium 20mg from markets and the inclusion of a dosage cup for the proper administration of this medicine. The agency also set the highest daily dosage of this medicine to 30mg for adults who weight over 35kg and, for children who weight less than 35kg, it recommended a dosage of 0.75mg/ Kg daily.
Here is the link to the reassessment result: http://bit.ly/2zMyuxu